Nebido 1000 mg 4 ml solution for injection Summary of Product Characteristics SmPC emc

The reason for this is the fact that injections are the most direct route to get testosterone in the bloodstream. In a Nebido injection, you’ll find that the injection site creates a natural reservoir of testosterone that slowly disperses throughout the weeks to provide an evenly-balanced treatment that won’t fizzle out after a few days. Painful swelling of one leg or sudden change in colour of the skin e.g. Turning pale, red or blue, sudden breathlessness, sudden unexplained cough which may bring up blood; or sudden chest pain, severe light headedness or dizziness, severe pain in your stomach, sudden loss of vision. Seek urgent medical attention if you experience one of these symptoms.

The way that Nebido works is that it is injected into your body, usually into a muscle within the body. When it is injected, it is stored within the body and is gradually released over a period of time. This provides an evenly distributed effect that increases the effectiveness of the injection. Nebido is most commonly used as steroids in USA a treatment method for men who are having a lack of testosterone on the NHS in the UK. Your doctor will measure your blood testosterone levels before starting treatment and during the early stages of treatment. Your doctor may give you the second injection after only six weeks in order to quickly reach the necessary testosterone level.

• I currently manage my own testosterone replacement therapy via the black market and have done so successfully since 2021.
• They are a private service and I received great treatment and excellent service from them.
• If your testosterone levels are high, your doctor may decide to give you injections less often.
• If they are unable to assist you, ask for a referral to someone that can.
• The most common side effects are acne and pain where the injection is given.

How Nebido Testosterone Injections Work

There is a pre-scored mark beneath the coloured point on the ampoule eliminating the need to file the neck. Prior to opening, ensure that any solution in the upper part of the ampoule flows down to the lower part. Use both hands to open; while holding the lower part of the ampoule in one hand, use the other hand to break off the upper part of the ampoule in the direction away from the coloured point. 5-ml brown glass (type I) ampoules, containing a fill volume of 4 ml.

Nebido is the only long-acting testosterone undecanoate injection providing physiological testosterone levels with only 4-5 injections per year. If you are suffering from severe heart, liver or kidney disease,treatment with Nebido may cause severe complications in the form of water retention in your body sometimes accompanied by (congestive) heart failure. Testosterone and derivatives have been reported to increase the activity of coumarin derived oral anti-coagulants. Patients receiving oral anti-coagulants require close monitoring, especially at the beginning or end of androgen therapy. Increased monitoring of the prothrombin time, and INR determinations, are recommended.

Are There Potential Side Effects?

Following intravenous infusion of testosterone to elderly men, the elimination half-life of testosterone was approximately one hour and an apparent volume of distribution of about 1.0 l/kg was determined. It also performs functions, e.g. in the skin, muscles, skeleton, kidney, liver, bone marrow, and CNS. Testosterone undecanoate is an ester of the naturally occurring androgen, testosterone. The active form, testosterone, is formed by cleavage of the side chain. The most frequently reported undesirable effects during treatment with Nebido are acne and injection site pain. Nebido should be permanently withdrawn if symptoms of excessive androgen exposure persist or reappear during treatment with the recommended dosage regimen.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If stored in cold conditions, bring the vial to room temperature before use. It is crucial to confirm these symptoms through thorough medical evaluations before starting therapy. Symptoms may include fatigue, low libido, erectile dysfunction, and decreased muscle mass.

No formal studies have been performed in patients with liver impairment. You will not be prescribed Nebido if you have ever had a liver tumour (see “Do not use Nebido”). I currently manage my own testosterone replacement therapy via the black market and have done so successfully since 2021.

Each ampoule / vial with 4 ml solution for injection contains 1000 mg testosterone undecanoate corresponding to 631.5 mg testosterone. Balance My Hormones helps men and women restore their hormones to optimal levels through bespoke TRT and HRT treatment plans. We use modern American treatment methods and have over 25 years of experience in hormonal health which is backed up by our very own GPhC pharmacy. It is important that you stay in communication with your medical professionals and you notify them if you are having any negative side effects. Testosterone which is generated by ester cleavage from testosterone undecanoate is metabolised and excreted the same way as endogenous testosterone. The undecanoic acid is metabolised by ß-oxidation in the same way as other aliphatic carboxylic acids.